Cell Culture/Upstream Processing

We work in our state-of-the-art cGMP-facilities with highly qualified and well-trained personnel and manufacture biopharmaceuticals for clinical studies and market supply.

Our Expertise

  • Clinical and commercial drug substance manufacturing
  • Manufacturing in stainless steel and single-use bioreactors
  • Cultivation methods: Fed-batch, continuous and perfusion mode
  • Cell banking: Production, testing and storage of master and working cell banks

Our Capacities

Your Benefits

  • Customized and cost-effective manufacturing
  • High degree of flexibility by multi-product cGMP facilities
  • Our experience with a wide variety of protein structures, scales and technologies
  • In-house manufacturing support services

Purification/Downstream Processing

The purification of proteins from cell culture supernatant is a crucial step in the production of active ingredients. We know the requirements for various therapeutic proteins such as monoclonal antibodies and fusion proteins and can reproduce reliable the efficiency and robustness of the process steps for your active ingredient.

Our Expertise

  • Chromatographic separation including anion/cation exchange, affinity, hydrophobe interaction
  • Filtration and extraction
  • Virus inactivation and removal
  • Protein modification

Your Benefits

  • High quality and fastest possible time to market
  • Our know-how in protein purification
  • Our experience with a wide variety of technologies
  • In-house manufacturing support services

Aseptic Filling

Our Expertise

  • Aseptic filling of proteins, peptides, and non-cytotoxic small molecules
  • For clinical supply
  • Aseptic liquid filling in vials
  • Lyophilization in vials
  • Labeling and packaging

Your Benefits

  • Our experience with a variety of substance classes
  • Manufacturing of low-volume products such as orphan drugs
  • Individual solutions
  • In-house manufacturing support services

Quality Control

Our Expertise

  • Comprehensive monitoring of all parameters for quality control
  • Analytical characterization of biopharmaceuticals
  • Drug product/drug substance release testing
  • Comparability and stability studies

Your Benefits

  • Ensuring purity, safety and stability of your product
  • Convenience of an analytical full-service
  • Extensive experience in analytics
  • Our know-how in stability testing